Antinuclear antibodies during procainamide treatment and drug acetylation.

Antinuclear Antibodies

knowledge of gene regulation, particularly in neoplastic cells, this deficit is striking. With our current understanding of chromosomal translocations, point mutations, and gene amplification in tumor cells, it is surprising to read that there is ". . . no difference between cancer and normal DNA . . ." (p. 130). The author spends a fair amount of time discussing possible mechanisms for the car...

Antinuclear antibodies in psychiatric illness: their relationship to diagnosis and drug treatment.

Antinuclear antibodies occurred more often and in higher titres in psychiatric patients than in controls. Anti-DNA antibodies were not found. We suggest that antinuclear antibodies may be drug-induced and that lithium carbonate may have a particular tendency to produce this reaction.

Antinuclear antibodies in systemic sclerosis

Antinuclear antibodies in rosacea patients

INTRODUCTION Rosacea is a common inflammatory disorder, characterized by a spectrum of facial manifestations. The clinical similarity to other dermatoses, like lupus erythematosus, might lead to misdiagnosis, particularly in patients with elevated antinuclear antibody titers. AIM To assess the frequency, titer and specificity of antinuclear antibodies in rosacea patients and correlate these f...

Antinuclear antibodies defining autoimmunity pathways

Immunofluorescent imaging has been a powerful technique in helping to identify intracellular nuclear and cytoplasmic molecules which are target antigens of autoantibodies in systemic autoimmune disorders. Patterns of staining can be correlated with molecules engaged in specific cellular functions and distributed in distinct cellular domains. Different autoimmune disorders have different profile...